A mystery evening runs differently from a board game. There is no turn order and nobody is eliminated — everyone reads the same evidence and argues about what it means. That makes it unusually good for a mixed group, because the person who never wins at Catan is often the one who spots the inconsistency.
The practical shape is simple. One person opens the case file and reads the briefing aloud. The evidence gets spread across a table so more than one person can look at once. Somebody keeps notes, because names and times start colliding about twenty minutes in. Then you argue, and eventually you commit to an answer.
Three to six people is the sweet spot. Two works but you lose the argument, which is most of the fun. Above six, people drift away from the table.